Yu Fang Selected Research

N- methyl- N- (3- ((2- (2- oxo- 2,3- dihydro- 1H- indol- 5- ylamino)- 5- trifluoromethyl- pyrimidin- 4- ylamino)- methyl)- pyridin- 2- yl)- methanesulfonamide

2/2017

Synthesis, biological evaluation, and molecular dynamics (MD) simulation studies of three novel F-18 labeled and focal adhesion kinase (FAK) targeted 5-bromo pyrimidines as radiotracers for tumor.

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Yu Fang Research Topics

Disease

53	Neoplasms (Cancer) 01/2022 - 06/2004
14	Hepatocellular Carcinoma (Hepatoma) 08/2022 - 05/2017
9	Infections 01/2022 - 01/2013
9	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2011
8	Inflammation (Inflammations) 10/2022 - 01/2017
8	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2012
7	Lung Neoplasms (Lung Cancer) 12/2018 - 06/2012
6	Hypoxia (Hypoxemia) 10/2022 - 03/2007
6	Chronic Hepatitis B 02/2022 - 01/2019
6	Carcinogenesis 01/2022 - 10/2013
5	Stomach Neoplasms (Stomach Cancer) 01/2021 - 11/2006
5	Virus Diseases (Viral Diseases) 01/2021 - 01/2013
4	Sepsis (Septicemia) 01/2022 - 01/2010
4	Cognitive Dysfunction 01/2022 - 02/2014
4	Schizophrenia (Dementia Praecox) 10/2021 - 10/2015
4	Respiratory Tract Infections (Respiratory Tract Infection) 09/2021 - 12/2019
4	Human Influenza (Influenza) 01/2021 - 01/2020
4	Hypersensitivity (Allergy) 01/2021 - 01/2014
4	Breast Neoplasms (Breast Cancer) 01/2021 - 03/2007
3	Brain Ischemia (Cerebral Ischemia) 04/2022 - 06/2017
3	COVID-19 01/2022 - 01/2021
3	Cough 01/2022 - 01/2020
3	Pain (Aches) 01/2022 - 01/2021
3	Hypertension (High Blood Pressure) 01/2022 - 01/2016
3	Liver Cirrhosis (Hepatic Cirrhosis) 12/2020 - 01/2020
3	Drug-Related Side Effects and Adverse Reactions 03/2019 - 07/2012
3	Esophageal Neoplasms (Esophageal Cancer) 01/2017 - 03/2012
3	Obstructive Sleep Apnea 10/2016 - 03/2013
2	Atrophy 10/2022 - 01/2022
2	Edema (Dropsy) 06/2022 - 02/2018
2	Lung Injury 06/2022 - 01/2018
2	Acute Lung Injury 06/2022 - 10/2020
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 03/2022 - 01/2021
2	Liver Failure 02/2022 - 01/2019
2	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 01/2022 - 12/2021
2	Hyperkalemia 01/2022 - 01/2022
2	Diarrhea 01/2022 - 01/2021
2	Epilepsy (Aura) 01/2022 - 01/2015
2	Ischemia 01/2022 - 04/2016
2	Carcinoma (Carcinomatosis) 01/2022 - 10/2020
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 01/2021
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2019
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2019
2	Wounds and Injuries (Trauma) 01/2022 - 12/2020
2	Rupture 01/2022 - 04/2013
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2021 - 12/2020
2	Metaplasia 12/2021 - 01/2019
2	Communicable Diseases (Infectious Diseases) 09/2021 - 01/2021
2	Obesity 01/2021 - 10/2013
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2020
2	Asthma (Bronchial Asthma) 01/2021 - 01/2018
2	Bacterial Infections (Bacterial Infection) 01/2021 - 01/2013
2	Lymphoma (Lymphomas) 01/2021 - 03/2019

Drug/Important Bio-Agent (IBA)

16	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 07/2014
15	Proteins (Proteins, Gene)FDA Link 06/2022 - 06/2004
11	Pharmaceutical PreparationsIBA 01/2022 - 01/2015
10	Long Noncoding RNAIBA 08/2022 - 01/2017
10	Biological ProductsIBA 01/2022 - 03/2012
8	Messenger RNA (mRNA)IBA 01/2022 - 10/2012
7	Biomarkers (Surrogate Marker)IBA 12/2021 - 03/2012
5	MicroRNAs (MicroRNA)IBA 01/2022 - 03/2012
4	LipopolysaccharidesIBA 06/2022 - 09/2018
4	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2022 - 02/2017
3	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2022 - 03/2007
3	Small Interfering RNA (siRNA)IBA 06/2022 - 03/2016
3	Peptides (Polypeptides)IBA 01/2022 - 01/2020
3	Insulin (Novolin)FDA Link 01/2022 - 04/2015
3	EnzymesIBA 01/2022 - 01/2018
3	VaccinesIBA 01/2021 - 12/2020
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 07/2009
3	Therapeutic UsesIBA 10/2020 - 02/2018
3	Phosphotransferases (Kinase)IBA 03/2018 - 08/2011
3	CurcuminIBA 01/2018 - 01/2015
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 06/2017 - 01/2011
3	LigandsIBA 10/2013 - 09/2002
2	salicylhydroxamic acid (SHAM)IBA 10/2022 - 01/2021
2	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2022 - 01/2018
2	GlucocorticoidsIBA 02/2022 - 01/2019
2	Monophenol Monooxygenase (Tyrosinase)IBA 01/2022 - 01/2018
2	Antipsychotic Agents (Antipsychotics)IBA 01/2022 - 11/2019
2	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2015
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2021
2	Liposomes (Liposome)IBA 01/2022 - 01/2020
2	CalciumIBA 01/2022 - 01/2021
2	N- (2- amino- 5- fluorobenzyl)- 4- (N- (pyridine- 3- acrylyl)aminomethyl)benzamideIBA 01/2022 - 12/2021
2	pyrimidineIBA 01/2022 - 03/2018
2	Circular RNAIBA 12/2021 - 01/2021
2	Capsules (Microcapsules)IBA 12/2021 - 04/2013
2	AntioxidantsIBA 09/2021 - 05/2020
2	Histones (Histone)IBA 01/2021 - 01/2020
2	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2021 - 01/2021
2	Calcium-Binding ProteinsIBA 01/2021 - 01/2017
2	Rituximab (Mabthera)FDA Link 01/2021 - 01/2021
2	Lysine (L-Lysine)FDA Link 01/2021 - 01/2021
2	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2021 - 01/2020

Therapy/Procedure

23	Therapeutics 02/2022 - 03/2002
10	Drug Therapy (Chemotherapy) 01/2022 - 11/2006
3	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021 - 01/2013
2	Renal Dialysis (Hemodialysis) 01/2022 - 06/2021
2	Length of Stay 03/2021 - 11/2017